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Enzo Biochem
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Biomol GmbH
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Promega
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Santa Cruz Biotechnology
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Image Search Results
Journal: Biology
Article Title: Genetic Activation of Locus Coeruleus Noradrenergic Neurons Modulates Cerebellar MF-GrC Synaptic Plasticity via Presynaptic α2-AR/PKA Signaling in Mice
doi: 10.3390/biology15050406
Figure Lengend Snippet: Optogenetic activation of LC noradrenergic neurons triggers facial stimulation-induced MF-GrC LTD via the PKA signaling cascade. ( A ) In the presence of D-APV (50 μM) and a potent PKA inhibitor, KT5720 (KT, 1 μM), representative traces show air puff stimulation (10 ms, 60 psi)-induced MF-GrC synaptic responses before (Pre) and after (Post) delivery of 20 Hz air puff stimulation in the control group (Control) and the optogenetic stimulation of the LC noradrenergic neurons group (Opti. Sti.). ( B ) Summary of data showing the time course of normalized N amplitude before and after delivery of 20 Hz stimulation (black arrow) in the control group (filled circles) and optogenetic stimulation of the LC noradrenergic neurons group (470 nm, 5 Hz, 60 pulses; blue arrow; open circles). ( C , D ) Bar graphs overlaid with individual data points illustrate the normalized amplitude ( C ) and AUC ( D ) of N before (Pre) and after (Post) delivery of 20 Hz stimulation in the control group and optogenetic stimulation of the LC noradrenergic neurons group. n = 8 recordings/8 mice per group. Opti. Sti.: optical stimulation.
Article Snippet:
Techniques: Activation Assay, Control
Journal: Cell reports
Article Title: Structural basis of TRPV5 regulation by physiological and pathophysiological modulators
doi: 10.1016/j.celrep.2022.110737
Figure Lengend Snippet: KEY RESOURCES TABLE
Article Snippet:
Techniques: Recombinant, Protease Inhibitor, Mutagenesis, Transformation Assay, Kinase Assay, Plasmid Preparation, Software